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ANALYSIS
27 SEP 2026
Medicine · outbreak response

In four months, Bundibugyo Ebola has recorded more than twice the cases of DR Congo's largest previous outbreak

DR Congo has confirmed 7,890 cases and 3,799 deaths since 15 May, against 3,470 cases and 2,287 deaths in the whole two-year Kivu epidemic of 2018-20. New cases have stopped accelerating, but they have not yet begun to fall.

7,890
Confirmed cases in DR Congo from 15 May to 23 September — 2.3 times the final Kivu 2018–20 total
3,799
Deaths among those cases, against 2,287 in the entire Kivu epidemic
40days
Of the response to pass 1,000 confirmed cases; the 2018 outbreak took about 235
The comparison

Past Kivu's final total inside three months

DR Congo and Uganda declared an outbreak of Bundibugyo virus disease, a form of Ebola, on 15 May 2026, and WHO declared it a public health emergency of international concern two days later.11 By 23 September DR Congo had reported 7,890 laboratory-confirmed cases, including 3,799 deaths.2 Uganda has reported 20 cases and two deaths, and single imported cases have been treated in France and Germany.1

The natural yardstick is the Ebola outbreak that began in North Kivu on 1 August 2018, the largest in DR Congo's history until now.26 It ran for almost two years, was declared over on 25 June 2020, and recorded 3,470 confirmed and probable cases and 2,287 deaths.7 The US Centers for Disease Control and Prevention (CDC) says the 2026 outbreak passed 1,000 confirmed cases within 40 days of the response starting; the 2018 outbreak took about 235 days.3

At day 77 the Kivu outbreak had 223 cases.8 The 2026 outbreak had 2,124 confirmed cases in DR Congo by day 616 and 6,757 by day 115,1 so it overtook Kivu's final total somewhere in between — within about three months of being declared.

Exhibit 01
Cumulative cases by day since each outbreak was declared
Source: WHO Disease Outbreak News and ECDC for 2026 (DR Congo, confirmed cases only); WHO Regional Office for Africa and CDC for 2018–20 (confirmed and probable cases). Day 0 is the date each outbreak was declared: 15 May 2026 and 1 August 2018. The Kivu points at day 235 (about 1,000) and day 365 (more than 2,600) are approximate. Lines join reported points only. Noodle News analysis.1237
Key finding. Counting only laboratory-confirmed cases, the 2026 outbreak has 2.3 times the cases and 1.7 times the deaths of the Kivu epidemic, which also counted probable cases. The different counting rules make the gap look smaller than it is, not larger.
The virus, in plain terms

What Bundibugyo is, and how it spreads

What it is. Ebola is not one virus but a family. Bundibugyo is one of three members known to cause large outbreaks in people; the other two are the Zaire and Sudan species. It is named after Bundibugyo district in western Uganda, where it was first identified in 2007.11 Before this year it had caused only two known outbreaks, in Uganda in 2007 and in DR Congo in 2012, with 131 and 62 confirmed cases respectively.10 The Kivu outbreak of 2018–20 was caused by the Zaire species, a different virus.

Where it comes from. Fruit bats are thought to be the natural home of Ebola viruses. People are usually first infected through contact with the blood or body fluids of an infected animal, such as a bat or a monkey.9 Genetic analysis indicates the 2026 virus is distinct from the 2007 and 2012 strains, which points to a fresh jump from animals rather than a leftover from an earlier outbreak.15

Symptoms. Illness starts 2 to 21 days after infection, usually suddenly: fever, extreme tiredness, muscle pain, headache and sore throat. Vomiting, diarrhoea and a rash tend to follow, and in some patients bleeding, for example from the gums or in the stool.9 The first clusters this year were among health workers in DR Congo, who had fever, vomiting, diarrhoea and in some cases bleeding.4

How it spreads. Between people, the virus passes through direct contact — via broken skin or the eyes, nose and mouth — with the blood, vomit, faeces or other body fluids of someone who is ill or has died, or with bedding and other objects contaminated by them. People are not infectious before their symptoms start. Carers, health workers and people who wash bodies at funerals face the highest risk.9

Treatment. There is no approved drug for Bundibugyo. Care centres on replacing lost fluids and salts and treating symptoms and other infections; improvements in that supportive care have raised survival in recent Ebola outbreaks.10 Since 2 July a WHO-sponsored trial, PARTNERS, has been testing whether an antibody treatment called MBP134 and the antiviral remdesivir, alone or together, improve survival.16 A health worker flown to Germany recovered after receiving both, but a single case cannot show whether the drugs worked.17

Vaccines. None is licensed against Bundibugyo. Since late August DR Congo has been giving Ervebo, the vaccine licensed against the Zaire species, to front-line workers under compassionate-use and research protocols.2819 Animal studies and limited human data suggest it may give some cross-protection.1018 Whether it works against this virus is not yet known.18 Bundibugyo-specific vaccines from Oxford University with the Serum Institute of India, and from Moderna, are in early safety trials.21

The pace

New cases have levelled off, at a high rate

Dividing the rise in confirmed cases by the days between reports gives a rough daily rate. It climbed from about 38 a day in June to 86 a day between mid-July and early September, then eased to 71 a day in the first three weeks of September.12 The Kivu outbreak averaged about 12 cases a day between roughly its 1,000th and 2,600th case, its busiest stretch in the figures used here.37

Exhibit 02
Average new confirmed cases per day in DR Congo, between reporting dates
Source: CDC MMWR (2 June), WHO Disease Outbreak News (1 July, 15 July, 7 September), ECDC (23 September). Each bar is the change in cumulative confirmed cases divided by the days between reports. The dashed line is the Kivu outbreak's average from about day 235 to day 365 (roughly 1,000 to 2,600 cases), confirmed and probable. Noodle News analysis.45612

Modelling points the same way. A peer-reviewed analysis estimated early growth at about 9% a day in late May, but warned that the figure was inflated by how quickly cases were being found.12 A preprint, not yet peer reviewed, estimates that each case was infecting about 2.9 others in mid-May and about 1.3 by early July.14 A second preprint puts the national figure close to 1 since early August: roughly, each case now replaces itself rather than multiplying. It also finds that the national average hides continued growth in one North Kivu health zone, and no clear decline in Ituri's two largest towns by case count.13

The outbreak is also still spreading geographically. By 7 September it had reached 61 health zones in six of DR Congo's 26 provinces, with Ituri the epicentre.1 ECDC reports that 83.4% of identified contacts were under follow-up on 23 September;2 the head of Africa CDC has said the response is falling short of the roughly 420,000 contacts that 7,000-plus cases imply.22

Deaths

Half of confirmed patients have died — or two in three, depending on the count

WHO puts the crude fatality ratio at 48.3% on 7 September.1 On 23 September figures it is 48.1%. That ratio counts about 2,125 people whose illness had not yet ended in death or recovery. Counting only the 5,765 cases with a known outcome gives 65.9%, the same as the Kivu outbreak's final ratio.27

Exhibit 03
Share of cases that died, by how the ratio is counted
Source: ECDC, DR Congo data to 23 September 2026 (3,799 deaths, 1,966 recoveries, 7,890 confirmed cases); WHO Regional Office for Africa for Kivu 2018–20 (2,287 deaths, 3,470 confirmed and probable cases). “Known outcome” divides deaths by deaths plus recoveries. Noodle News analysis.27

Neither 2026 measure is the true figure. The crude ratio understates it while many patients are still ill; the known-outcome ratio overstates it if recoveries are recorded more slowly than deaths. A July preprint produced estimates from 37.5% to 67.3% from the same data depending on the method.14 The Kivu ratio is not a clean comparison either, because probable cases are identified largely after death, which pushes it up.

Young children fare worst. WHO's Africa office reports that children make up nearly one in four confirmed cases but almost one in three deaths, and that more than 60% of confirmed cases in children under five have died.18

Why it differs

A slower start to the response, and no matched tools

These are the explanations offered in the research so far; none has been tested as a cause. First, detection: a preprint estimates transmission began around 19 April, 16 days before WHO was alerted,15 and the first suspected case was a health worker, with at least four health workers dead before the outbreak was confirmed.27 Second, tools: responders in Kivu had a vaccine matched to the virus, eventually given to more than 320,000 people,23 and trial-proven antibody treatments that WHO has since recommended.25 In 2026 neither existed at the start. Third, setting: this is the first Bundibugyo outbreak to sustain spread in a major city, Bunia,15 and it is unfolding in a region of armed conflict and mass displacement.27

What we don't know

The true size of the outbreak. Confirmed counts depend on testing. An early jump in reported cases coincided with the clearing of a backlog of samples,10 and a preprint argues that a flat count alongside a rising death ratio in early July fits laboratories running at capacity rather than slower spread.14

Whether the levelling-off is real. The national reproduction number near 1 comes from a preprint that has not been peer reviewed, and it masks local growth.13

Whether Ervebo protects against Bundibugyo. A 20,000-person study, BRAVO, began in Bunia on 19 September and is expected to run for nine to 12 months.20 No results from the PARTNERS treatment trial have been published.16

Where it stands
61
Health zones affected in DR Congo, across six provinces, to 7 September
893
Patients in isolation in DR Congo on 23 September
83%
Of identified contacts under follow-up, 23 September
1,966
Confirmed patients recovered in DR Congo, to 23 September
Caveat. The strongest objection to the headline comparison is that the two outbreaks were not counted the same way or on the same clock. Kivu's total includes probable cases and 2026's does not, which flatters Kivu. But day 0 is each outbreak's declaration, and the two were detected at different stages, so a matched day is not a matched point in each epidemic. The size gap is large enough to survive both caveats; the speed ratio should be read as approximate.312
Go deeper
Method. Day 0 is the date each outbreak was declared: 15 May 2026 for Bundibugyo virus disease and 1 August 2018 for the North Kivu outbreak. The 2026 series counts laboratory-confirmed cases in DR Congo only, excluding Uganda and the patients treated in France and Germany; the 2018–20 series counts confirmed and probable cases, as reported at the time. Case definitions were not harmonised and nothing has been adjusted. Kivu's day-235 value (about 1,000 cases) is CDC's approximate milestone, and its day-365 value (more than 2,600) is WHO's lower bound, so both are plotted as approximations. Kivu's final total is given as 3,470 cases and 2,287 deaths by WHO; a later analysis of Ministry of Health data gives 3,481 and 2,299,24 a difference that does not affect any comparison here. The WHO Africa situation report of 9 August (4,381 confirmed cases) was not used, because its extract did not make clear whether the total includes Uganda. Daily rates are the change in cumulative confirmed cases divided by the days between reports, which averages over reporting delays and backlog clearance. The known-outcome fatality ratio is deaths divided by deaths plus recoveries. All derived figures were computed in code and checked against the printed source values. Preprints (sources 13–15) have not been peer reviewed and are identified as such in the text.
Sources. Numbered, with tier shown; each inline citation points here.
  1. T1World Health Organization — Disease Outbreak News: Ebola disease caused by Bundibugyo virus, Democratic Republic of the Congo, data to 7 Sep 2026. who.int. Retrieved 27 Sep 2026.
  2. T2European Centre for Disease Prevention and Control — Ebola disease outbreak in the Democratic Republic of the Congo and Uganda, update of 24 Sep 2026 reporting DR Congo data to 23 Sep. ecdc.europa.eu. Retrieved 27 Sep 2026 (via search extract).
  3. T1US Centers for Disease Control and Prevention — Ebola outbreak: current situation. cdc.gov. Retrieved 27 Sep 2026 (via search extract).
  4. T1Zomahoun DL and others (CDC) — Notes from the field: outbreak of Ebola disease caused by Bundibugyo virus, DR Congo and Uganda, May 2026. MMWR 75(22). cdc.gov. Retrieved 27 Sep 2026.
  5. T1World Health Organization — Disease Outbreak News: Bundibugyo virus disease, DR Congo and Uganda, 3 Jul 2026. who.int. Retrieved 27 Sep 2026.
  6. T1World Health Organization — Disease Outbreak News: Bundibugyo virus disease, DR Congo and Uganda, 17 Jul 2026. who.int. Retrieved 27 Sep 2026.
  7. T1WHO Regional Office for Africa — Heroes of the Ebola response (final Kivu totals; one-year figures). afro.who.int. Retrieved 27 Sep 2026.
  8. T1WHO Regional Office for Africa — Highlights of Ebola virus disease preparedness in Uganda, updates 21, 28 and 37 (DR Congo data to 29 Aug, 26 Sep and 17 Oct 2018). afro.who.int. Retrieved 27 Sep 2026.
  9. T1World Health Organization — Ebola virus disease fact sheet. who.int. Retrieved 27 Sep 2026 (via search extracts of WHO fact sheet and FAQ text).
  10. T1New England Journal of Medicine — Bundibugyo virus disease in 2026: clinical and public health responses (review), 24 Jun 2026. nejm.org. Retrieved 27 Sep 2026 (via search extract).
  11. T2The Lancet Infectious Diseases — Key facts about the Bundibugyo virus outbreak, 27 May 2026. thelancet.com. Retrieved 27 Sep 2026 (via search extract).
  12. T1New Microbes and New Infections 72:101811 — R0 of Bundibugyo virus disease and the critical issue of case ascertainment in the DR Congo, Jul 2026. pmc.ncbi.nlm.nih.gov. Retrieved 27 Sep 2026 (via search extract).
  13. T2Verheyden JGL, Mudogo CN — Sub-national heterogeneity in the time-varying reproduction number during the 2026 Bundibugyo outbreak (preprint, not peer reviewed), medRxiv, Aug 2026. medrxiv.org. Retrieved 27 Sep 2026 (via search extract).
  14. T2Evidence for a detection ceiling in the 2026 Bundibugyo virus disease epidemic in DR Congo (preprint, not peer reviewed), medRxiv, Jul 2026. medrxiv.org. Retrieved 27 Sep 2026 (via search extract).
  15. T2Sixteen days undetected: growth dynamics in the 2026 Bundibugyo virus disease outbreak, DR Congo (preprint, not peer reviewed), medRxiv, Aug 2026. medrxiv.org. Retrieved 27 Sep 2026 (via search extract).
  16. T1World Health Organization — Patient enrolment begins in a trial to identify the first effective treatments for Bundibugyo virus disease, 2 Jul 2026. who.int. Retrieved 27 Sep 2026.
  17. T1Uhrig A and others — A case of Bundibugyo virus disease treated with monoclonal antibodies and remdesivir. Nature Medicine, 2026. nature.com. Retrieved 27 Sep 2026 (via search extract).
  18. T2UN News — Ebola vaccine trial begins in DR Congo, 21 Sep 2026, reporting WHO and WHO Africa statements. news.un.org. Retrieved 27 Sep 2026.
  19. T3Associated Press, via TimesLIVE — DRC begins Ebola vaccinations for health workers in the epicentre of the outbreak, 20 Sep 2026. timeslive.co.za. Retrieved 27 Sep 2026.
  20. T3Xinhua, via GlobalSecurity.org — DR Congo expands Ebola vaccination to Ituri, over 3,700 people vaccinated, Sep 2026. globalsecurity.org. Retrieved 27 Sep 2026.
  21. T3Medical News Today — Ebola: treatments, vaccine trials for unchallenged viral strain begin, 5 Aug 2026, reporting a WHO briefing. medicalnewstoday.com. Retrieved 27 Sep 2026.
  22. T3Al Jazeera — DR Congo's Ebola outbreak spreads to two new health zones, WHO says, 25 Sep 2026. aljazeera.com. Retrieved 27 Sep 2026.
  23. T3Médecins Sans Frontières Australia — The Ebola outbreak in the Democratic Republic of Congo (end-of-outbreak figures). An operational responder, and therefore an interested party. msf.org.au. Retrieved 27 Sep 2026.
  24. T1Scientific Reports — Analysis of individual-level data from the 2018–2020 Ebola outbreak in DR Congo, 2022. nature.com. Retrieved 27 Sep 2026.
  25. T2Ensuring children's inclusion in the Bundibugyo Ebola response: striving to do better this time (commentary), 2026. ncbi.nlm.nih.gov. Retrieved 27 Sep 2026 (via search extract).
  26. T1US Centers for Disease Control and Prevention — History of Ebola outbreaks. cdc.gov. Retrieved 27 Sep 2026.
  27. T1Past lessons for the 2026 Bundibugyo virus outbreak: filovirus infection prevention in conflict-affected settings (review), 2026. pubmed.ncbi.nlm.nih.gov. Retrieved 27 Sep 2026 (via search extract).
  28. T3Al Jazeera — DRC begins vaccinating front-line healthcare workers against Ebola, 28 Aug 2026. aljazeera.com. Retrieved 27 Sep 2026.
Corrections. None. Material corrections will be logged here with date.
Figures to 27 Sep 2026. Noodle News · v1.0 · bundibugyo-passes-kivu.